Custom Organic & Inorganic Synthesis

Custom Organic & Inorganic Synthesis

20 Years of Custom Organic & Inorganic Synthesis Experience

 

Labron® has more than 20 years of custom synthesis experience as a chemistry outsourcing partner to the pharmaceutical and biotechnology industries. We provide a full range of contract research and manufacturing services, including the custom synthesis of new chemical entities (NCE’s) through commercial cGMP manufacture of active pharmaceutical ingredients (API’s), DEA Controlled Substances (Schedules I-V) and their chemical intermediates. Our highly qualified staff of Ph.D. chemists will follow your project in our facilities from discovery through commercialization, providing an unparalleled level of service throughout the R&D, scale-up and manufacturing process.

• Custom Synthesis of NCE’s
• Rapid Scale-Up of Discovery Leads
• Multi-Step Synthetic Routes
• Controlled Substances Manufacture (DEA Schedules I-V)
• Chemical Process Development
• Process Validation
• cGMP Manufacture of Clinical Trial Materials
• cGMP Manufacture of Commercial API’s
• Technology Transfer
• Analytical Method Development and Validation
• Customer Audit Support
• Customized Packaging

Labron Custom Synthesis offers our customers a unique experience, combining the personalized service and responsiveness of a mid-size company with the resources, logistics, and technical depth of much larger companies.

 

Building blocks for combinatorial chemistry

Labron® has been using the wide range of established synthesis methods to create building blocks for combinatorial chemistry for the last five years. The range of highly-reactive compounds is growing day by day. For further information, please contact our chemists.

Single-step and multi-step synthesis

Many of our standard products have been developed according to our customer’s demand and ideas. They have been integrated into our continuously-growing product range of specialty chemicals and biochemicals. A lot of products used in diagnostics, biotechnical productions and chemical manufacturing processes are listed in our biochemicals catalog.

Research and Production Facilities

 

Our inspected facilities are designed and engineered to accommodate projects ranging from a multi-gram custom synthesis for drug discovery through multi-ton cGMP manufacturing. Utilizing a wide range of temperatures, pressures, and other reaction parameters, our kilo lab, pilot, and production reactor capacity allows the greatest flexibility in scouting the most efficient synthetic route for your particular molecule.

• Full Glassware R&D and Kilo Lab Synthesis Suites
• Complete On-Site Analytical Support
• 1200+ Gallon Total Reactor Capacity
• Multi-Purpose Glass-Lined Reactors from 20 to 500 Gallons
• Stainless Steel 50 Gallon Reactor
• Temperature Capability from -15°C to 250°C
• High-Pressure Autoclave Capacity
• High-Efficiency Distillation and Fractionation
• High-Vacuum and Inert Atmosphere Chemistry and Purification
• Vacuum Oven Drying for Solids
•Custom Blends and Formulations

 

Synthesis elaboration from concept to start-upM

Due to the small size of our company we are very flexible, having short lines of communication and a strong focus on our customer‘s demand. So we are in the position to develop new products in a short time. Our experience with chemical techniques, practiced continuously with the existing products, is of added value to our customers.

We are in a position of having well-equipped laboratories, where we can carry out most of the standard organic and inorganic synthesis methods in quantities of some milligrams to multi kilograms.

The preparation of chemicals is always performed with utmost care under the guidelines of our quality control. The products are controlled by analytical methods like HPLC, TLC and NMR as well as by chemical analytical methods. This enables us to ensure the highest purity of the products and to fulfill the specifications of our customers.

The attached list of chemical processes will show you the wide range of reactions that we are able to apply to the synthesis of our products.

Please do not hesitate to contact us for quotations on our products. Enquiries will always be treated confidentially.

Summary of the most important procedures that we can carry out in our laboratories:

• Acetylation
• Alkylation
• Amination
• Asymmetric Synthesis
• Catalysis
• Chlorosulfonation
• Condensations
• Diazotization
• Diels-Alder
• Esterification
• Friedel-Crafts
• Halogenation
• Heterocycles
• Hydrogenation
• Hydrolysis
• Main-Group Chemistry
• Organometallics
• Oxidation
• Reduction
• Sulfonation
•Suzuki Coupling

and many more…